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This series includes both professional and personal correspondence received; carbon copies of correspondence sent; and collected research materials in addition to letters. The correspondence is with colleagues from across the United States and abroad; citizens with inquiries regarding plants, such as roots in a basement; students regarding grades, course work, and recommendations; as well as family and friends including greeting cards. Some correspondence is typed, some handwritten, some on mimeographed pages, and some on postcards and slips of paper. Subjects include discussions of publications and orders for publications such as The Flora of West Virginia, Wild Flowers of West Virginia, and Spring Wild Flowers; content and business for the journal Castenea; discussions and notifications of botanical species' identification and request for specimens; WVU academic matters and WVU Department of Biology business; and family and other personal matters including letters and flyers regarding the Disciples of Christ Church and the First Christian Church in Morgantown where Dr. Core was a member. Of significance are letters from botanists P. D. (Perry Daniel) Strausbaugh, 1886-1965, and H. A. (Harry Ardell) Allard, 1880-1963. An envelope of addresses on slips of paper, torn from envelopes, and business cards is included in this series.

Series 1: Correspondence, 1827-1913, chiefly contains letters written to Siram P. Henkel with correspondents including members of the Koiner/Coiner family of Augusta County, the Miller family of Winchester, and the Rupert family of Augusta County. The correspondents report on family and community news, marriages, health and illnesses, deaths, weather, harvest and planting updates, crop yields, and include fellow merchants requesting advice on the market of certain goods and numerous requests for Dr. Henkel's pills. Of particular interest are the letters written to Siram by his sons Lewis and Luther while serving in the American Civil War. The sons, and Luther in particular, write about camp life and general updates related to the war. In a December 21, 1861 letter to his father, Lewis P. Henkel writes from Winchester and mentions General Stonewall Jackson. He also refers to General Gilbert S. Meem as "Genl. Drunk."

Series 1: Correspondence, 1830-2011, is comprised of more than 300 individual letters. The majority of the earlier ones involve Sarah "Sallie" Scott Bassett and/or her husband R.H. Bassett. Together their combined correspondence comprises eight folders and spans the years 1850-1913.

Series 1: Correspondence, 1846-1894, is comprised almost exclusively of correspondence addressed to Bettie McCoy Cushing, with most letters written by her husband Edwin Cushing, her mother Jane Carson McCoy, and her cousin Ellie (also signed Ella) in Winchester. A small group of letters from Robert Cabell Anderson (1854-1924) to his future wife Katie Cushing Anderson, daughter of Edwin and Betting Cushing, are included. Additional family members present in the correspondence (as either author or recipient) include Judge Joseph Carson (1806-1871) and Judson McCoy. All correspondence is arranged by recipient.