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The John A. Owen, Jr. Papers consist of 15 boxes of archival material including letters, research notes, and documentation, and other items which reflect his professional activities from 1951-1995. The materials especially focus on diabetes, obesity, and endocrinology research; the relationship between pharmaceutical companies and physicians; federal regulations on prescription writing; and pharmacist-physician interaction. This collection is of special interest to scholars interested in the University of Virginia's clinical investigation during the 1960s-70s on diabetes and endocrinology; the relationship between pharmaceutical companies (and other organizations sponsoring basic research) and physicians; the effect of and response to federal legislation of the early 1970s which regulated prescription writing; the role of the pharmacist and their relationship to the physician; the interaction of the University of Virginia's department of medicine with the hospital's lab/pathology department; and the use of free samples from drug companies.

The materials mostly focus on Walther Riese's professional work and life after imigrating to the United States. There are also materials related to his personal life, predominantly in Series 2 and 5. Some materials of and by Hertha Pataky Riese are included, primarily in Series 4. The majority of the collection materials are in English, with some in German and French. The papers are arranged into seven series.

Artificial collection of papers relating to various cities in the Commonwealth of Virginia.

The Francis H. Fife papers (1947-2015; 168.4 cubic feet) document the personal and professional life of Mr. Fife with an emphasis on his civic and community interests. Types of materials include reports, meeting minutes, correspondence, memoranda, journals, and some family documents. The collection is organized into three series: Oak Lawn 1, Oak Lawn 2, and Westview.

The papers of S.F. Bill Royall, Jr. contain a variety of personal material and ephemera, much of it related to Williamsburg, Virginia. The collection includes samples of printing from Bill Royall's press relating to Williamsburg organizations and events such as tags, calendars, posters, programs, stickers, flyers, bulletins and other items.