- John T. Parsons Papers11,295
- Rick Boucher Papers6,327
- Fries Textile Plant Records5,424
- Episcopal Diocese of Southwestern Virginia Records5,394
- M. Rupert Cutler Papers4,186
- Records of the Office of the President, Julian A. Burruss2,950
- Records of the Office of the President, T. Marshall Hahn, Jr.2,935
- Records of the Office of the Vice President for Administration, Stuart K. Cassell2,499
- Pocahontas Mines Collection2,405
- Robert E. Marshak Papers2,204
- Samuel Herrick Papers2,167
- Farrier Family Papers1,946
- Smithey & Boynton, Architects & Engineers Records1,818
- Virginia Academy of Science Records1,809
- Records of the Office of Academic Affairs, Leslie F. Malpass, Alfred Krebs, and Donald C. Darnton1,752