- Adolphus P. Howard Papers, 1850/19381
- Adolphus P. Howard Papers, 1854/19041
- Baltimore and Ohio Railroad Surveyors Scrapbook, 1900/19101
- Fletcher Brock Papers, 1851/18531
- George McCandless Porter (1835-1864) Papers, 1849/18641
- John Pendleton Kennedy (1795-1870) Papers, 1829/18621
- Louis H. Draper Artist Archives (VA-04), 1945/20052
- Maria Schwald, Diary Regarding Cruise Along the Ohio River, 1935/19521
- Ohio Valley Floods Papers, 1913/19711
- R.H. Hendershot Shipping Bills, 1850/18541
- Richard H. Brown Revolutionary War Map Collection, 1740/17991
- Shelby Family Papers, 19621
- Stanton C. Crawford, Collector, Papers, 1842/19641
- Sunderman Family Genealogy and History, 19871
- William Reynolds Diary, 18411