- Armistead Boothe Papers (MS164), 1803/19901
- Elrich W. Murphy Photograph Collection (MS415), 1940/19691
- Esther Holliday Green Collection (MS073), 1859/19821
- Frank Snowden Hopkins Notes (MS270), 1968/19741
- Gaines-Hodge Family Bible (MS414), 18841
- Historic House Tours Collection (MS059), 1931/20171
- John Thomas Ricketts Papers (MS071), 1787/19041
- Mary Crawford Powell Collection (MS236), 19871
- Ruth Kaye Collection (MS029), 1970/20102
- Shakes Letter Collection (MS005), 1778/20153
- William Gregory Family Papers (MS417), 1771/19931