- Robert E. Lee Family papers, 1792/1935, bulk 1833/18705
- Philip S. Hench Walter Reed Yellow Fever Collectioncirca 1800-circa 1998
bulk 1863-19744
- Andrew Edmiston Jr. (1892-1966) Papers, 1916/19481
- C-SPAN records, 1809/2012, bulk 1978/20121
- Calendar Collection, 1980/20051
- Charles James Faulkner (1806-1884) Papers, 1786/18781
- Frank Hereford (1825-1891) Correspondence, 1866/18921
- Frank Hereford (1825-1891) Correspondence, 1874/19011
- George Cookman Sturgiss (1842-1925) Papers, 1879/19101
- George H. McGrew Papers, 1865/18851
- George Jackson (1757-1831) Letter, 18031
- Harry C. Woodyard (1867-1929) Papers, 1910/19291
- Howard Sutherland, U.S. Senator for West Virginia, Correspondence, 1914/20221
- Hugh Ike Shott Papers, 1858/19541
- Izetta Jewel Brown Miller (b.1883), Clippings and Photographs, 1908/19731