- Margaret Venable (nee Dickinson) letters, 1833/19181
- Paul L. Grier Vertical Files, 1775/19881
- Photo album, 1936/19411
- Robert E. Lee Family papers, 1792/1935, bulk 1833/18705
- Royal E. Cabell Jr. Papers, 1992/19991
- Samuel Stanhope Smith Lectures, 1805/18111
- Science Building Papers (Gilmer Hall), 1941/20061
- Shelton H. Short, III papers, 1965/19741
- Student Lecture Notes and Exercise Books, 1828/18831
- The Voice of Prince Edward County, 1965/19691
- Topography Maps collection, 1984/20061
- Venable Family Collection, 1886/19421
- William H. Whiting Papers, 1890/19201