- Blake W. Corson, Jr., Papers, 1861/1984, bulk 1934/197936
- Brown Family papers, 1872/19191
- Carol Barton papers, 1973/202015
- Charles Goodsell Collection, 1982/200157
- Charles Willis Cassell Family Papers, 1883/19508
- College of Integrated Science and Technology (CISAT) records, 1987/20041
- Congressman Nick Joe Rahall II Papers, 1970/20151
- David A. Martin papers, 1973/20152
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/201614
- Dorothy Alexander Architectural Collection, 1939/19942
- ESPN College GameDay posters, 20153
- Edward G. Carson Papers, 1924/2004, bulk 1970/200041
- Eleanore Pettersen Architectural Collection, 1915/2003, bulk 1950/200061
- Ellen V. Nash papers, 1928/19901
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969207