- Clement Dixon Johnston Papers,23
- Cline M. Koon, Compiler, Koon Family Records4
- College of Agriculture and Life Sciences (CALS) Collection,4
- Dan H. Pletta Papers16
- David H. Sutton, Compiler, Research Papers regarding Helvetia, West Virginia3
- David Weimer, Collector, Seneca and Houze Glass Records19
- Davis & Davis Law Firm Records21
- Davis Coal and Coke, Coal Mining and Railroad Company, Records28
- Dolores Fleming, Research Papers regarding the Glass Industry, South Park Homes, and Other Topics3
- Don Knotts, Actor, Scripts, Sound Recordings, and Other Material11
- Dr. William A. Neal Papers10
- Earl Palmer Appalachian Photograph and Artifact Collection1
- Earl W. Kennedy, Mine Inspector, Coal Company Mine Inspection Records8
- Early Records of the Mount Vernon Ladies' Association96
- Emory L. Kemp Papers regarding Industrial History10