- Bessie Rowland James Papers, 1800/19722
- Betty Lou Ramsey, Professor of Interior Design, Papers, 1910/201543
- Blair family papers, 1821/194940
- Bradley H. Patterson, Jr. papers, 1943/201740
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/1953256
- Brooke County (W. Va.) Court Records and Miscellaneous Papers, 1780/1918348
- Brooke Family Papers, 1814/1990, bulk 1880/19602
- Carl B. Allen Papers Regarding Early Aviation, 1918/19713
- Carl George Krieger Papers, 1930/196814
- Charles H. Ambler (1876-1957) Papers, 1913/19573
- Charles Peters, Editor and Author, Papers, 1975/201652
- Charles Vandersee papers, 1974/19962
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20184
- Christopher Kolawoski newspaper collection, 1946/195110
- Clarence L. Musgrave Papers, 1839/19371