- Sally H. Thomas papers1
- Sally Jane Brown, Artist, Collection6
- Sam McColloch, Compiler, Three Manuscripts regarding Family History, Artists, and Fighter Pilot1
- Samuel F. Harsh Family, Genealogy, Photographs, and Artifacts1
- Samuel Spencer Stone, Compiler, Stone Family Papers1
- Samuel Vaughan Wilson Papers65
- Sarah Pillsbury Harkness Architectural Collection2
- Schola Cantorum Records18
- School of Architecture student records from Professor Michael Bednar courses2
- School of Business records7
- School of Theatre and Dance Records2
- Scott Donaldson Papers2
- Scottish Coalition USA Archives4
- Scrapbooks2
- Senator John D. (Jay) Rockefeller IV papers681