- E. Cabell Brand collection, 1992/20061
- E. Louise Righman, Genealogist, Research Materials, 1990/20221
- E. Maria Roth Architectural Collection, 1940/20107
- E.T. Estlack, U.S. Department of Agriculture, Soil Conservation Service, West Virginia Records, 1896/2004, bulk 1969/19951
- Earl Gregg Swem Library records, 1920/202416
- Earl W. Kennedy, Mine Inspector, Coal Company Mine Inspection Records, 1974/20132
- Earl and Jewell Ratliff Collection, 1860/2013, bulk 1920/19904
- Earle K. Shawe papers, 1938/20031
- East German poster collection political series1
- East German poster collection political series, 1943/20092
- EcoTheater Papers and Maryat Lee Diaries, 1950/20091
- Edgar H. and Beth N. Rossheim Papers, 1938/20051
- Edith McChesney Ker papers, 1948/200353
- Edith Moore Sprouse Papers (MS313), 1960/20034
- Edith R. White Papers, 1923/201012