- SOCA records for the outreach program to Garrett Square 1996-19995
- Sallie Bennett Papers regarding World War I Flying Ace Louis Bennett, Jr.2
- Sally H. Thomas papers61
- Sally Jane Brown, Artist, Collection4
- Sally Waldner Bould Stan Architectural Collection2
- Sam McColloch, Compiler, Three Manuscripts regarding Family History, Artists, and Fighter Pilot1
- Sam McColloch, Photographer, Photographic Prints5
- Sam Sadler papers28
- Sam di Bonaventura papers11
- Samuel F. Harsh Family, Genealogy, Photographs, and Artifacts1
- Samuel Spencer Stone, Compiler, Stone Family Papers4
- Samuel Vaughan Wilson Papers164
- Sanborn Insurance Atlas, Williamsburg, Virginia Collection1
- Sarah Bonwell Hudgins Foundation Records3
- Sarah Pillsbury Harkness Architectural Collection3