- Allan Blank Papers, 1958/20091
- Andrew Kohen papers, 1977/20061
- Audrey Emmons Architectural Collection, 1974/19972
- Black Women at Virginia Tech Oral History Project Records, 1967/2000, bulk 1994/20004
- Congressman Nick Joe Rahall II Papers, 1970/20151
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20168
- Edward G. Carson Papers, 1924/2004, bulk 1970/20006
- Faculty Senate Minutes, 1969/20072
- Furious Flower Poetry Center Records, 1970/20242
- George Conoly Phillips Papers, 1909/20102
- Linwood H. Rose papers, 1949/2009, bulk 1985/20091
- Michael J. Stolee Papers, 1964/200910
- Records of the Board of Visitors, 1908/20103
- Records of the Faculty, 1942/20141
- Records of the Virginia Cooperative Extension, 1862/19976