- Beverly Willis Architectural Collection, 1954/199911
- Black Women at Virginia Tech Oral History Project Records, 1967/2000, bulk 1994/20007
- Black, Kent, and Apperson Family Papers, 1779/19841
- Blacksburg Baptist Church Records, 1894/20074
- Blair-Weindel-Schrader Family Papers, 1943/19983
- Blanche Lemco van Ginkel Architectural Collection, 1956/20137
- C. David Loeks Papers, 1947/19975
- California Women in Environmental Design Records, 1990/19942
- Campus Guide Virginia Tech, 19901
- Carmen Espegel Alonso Architectural Collection, 1985/20041
- Carol O'Neale Culnan Architectural Collection, 1966/20165
- Carrie T. Sibold Family Papers, 1912/1990, bulk 1974/19904
- Carter/Cash Family Collection, 1940/20095
- Charles C. Richardson Papers, 1865/19962
- Charles F. McKenna Collection, 1861/19982