- U.S. Board of Geographic Names files of the Virginia State Archivist,1
- U.S. Forest Service, George Washington National Forest, Dry River District records3
- UR's 175th Anniversary Collection3
- USS Hyades Shipmates' Reunion Collection1
- USS Vulcan (AR-5) Collection20
- USS West Virginia Papers1
- USS West Virginia, Navy Uniform of Granville R. Williams1
- USS West Virginia, Records Regarding Bell, Clapper, and Mast1
- USS West Virginia, Scrapbook and Memorabilia1
- USS West Virginia, Scrapbook and Other Material of William Hand1
- Ulysses Grant Carter, Collector, Papers, Photographs, and Movie Films1
- Union Baptist Church Records, Hopewell, Virginia1
- Unitarian Universalist Church of Norfolk Records114
- Unitarian Universalist Fellowship of the New River Valley Records2
- United Daughters of the Confederacy Records (MS155)2