- U.S. Board of Geographic Names files of the Virginia State Archivist,, 1966/20121
- U.S. Forest Service, George Washington National Forest, Dry River District records, 1917/19943
- UMWA, Miners Right To Strike Committee Records, 1976/1978, bulk 1977/19781
- UR's 175th Anniversary Collection, 1997/20083
- USS Dwight D. Eisenhower Commemorative Envelopes, 19772
- USS Hyades Shipmates' Reunion Collection, 1940/20121
- USS Vulcan (AR-5) Collection, 1898/198513
- USS West Virginia Papers, 1967/19881
- USS West Virginia, Navy Uniform of Granville R. Williams, 1941/20011
- USS West Virginia, Records Regarding Bell, Clapper, and Mast, 1967/2002, bulk 1982/19911
- USS West Virginia, Scrapbook and Memorabilia, 1941/19911
- USS West Virginia, Scrapbook and Other Material of William Hand, 1934/1988, bulk 1934/19371
- Union Baptist Church Records, Hopewell, Virginia, 1935/20071
- Unitarian Universalist Church of Norfolk Records, 1866/2011, bulk 1950/1990109
- Unitarian Universalist Fellowship of the New River Valley Records, 1958/19872