- Charles L. Sampson Collection (MS126), 1841/19866
- Civitan and Civinette Clubs of Alexandria Collection (MS038), 1942/19782
- Curtin Family Papers (MS101), 1885/20004
- Delos H. Smith Collection (MS307), 1900/19501
- Dickman Collection (MS069), 1968/19851
- Edith Moore Sprouse Papers (MS313), 1960/20036
- Elanora Peake Zint Collection (MS345), 1924/20061
- Eleanor Lee Templeman Collection (MS061), 1810/199034
- Esther Holliday Green Collection (MS073), 1859/19824
- Ethelyn Cox Collection (MS287), 1956/19805
- Florence Davidson Collection (MS318), 1856/19832
- Glasgow Photo Collection (MS349), 1900/19791
- Historic Alexandria Foundation Records (MS070), 1949/19957
- Historic House Tours Collection (MS059), 1931/20171
- James B. Lynch Collection (MS022), 1974/19931