- Allan Blank Papers, 1958/20091
- Alumni Association Records, 1924/20161
- Black Women at Virginia Tech Oral History Project Records, 1967/2000, bulk 1994/20002
- Dennis Pluchinsky collection on terrorism and counterterrorism, 1956/20163
- Edward G. Carson Papers, 1924/2004, bulk 1970/20001
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/19691
- Ernest M. Dickerman papers, 1904/20052
- F. Ludwig Diehn Papers, 1904/19901
- Faculty Senate Minutes, 1969/20071
- George Conoly Phillips Papers, 1909/20102
- George Washington National Forest oral histories, 19941
- Linwood H. Rose papers, 1949/2009, bulk 1985/20091
- Ralph Cohen papers, 1940/20131
- Records of the Board of Visitors, 1908/20103
- Records of the Faculty, 1942/20141