- C and O for Progress (map), 1947/19721
- C-SPAN records, 1809/2012, bulk 1978/20126
- C. Barrett Graham papers, 1967/20161
- C. David Loeks Papers, 1947/199713
- C. Edwin Baker Papers, 1886/2013, bulk 1970/20091
- C. Ernest Edgar III papers, 1956/20101
- C. Eugene Rowe Papers, 1949/198714
- C. F. Tucker Brooke (1883-1946) Papers, 1870/1989, bulk 1895/19451
- C. Harrison Mann, Jr. papers, 1832/1979112
- C. Harrison Mann, Jr. papers, 1950/19771
- Cadet Life, Organizations, and Activities, 18452
- Calder Smith Sherwood, III Papers, 1899/197636
- Calendars Collection, 1910/20131
- Caley Family Papers, 1895/19686
- Calvert Walke Tazewell Papers, 1900/199731