- Carrie T. Sibold Family Papers, 1912/1990, bulk 1974/19901
- Charles S. Worley, Jr., Collection, 1950/19821
- Christiansburg-Blacksburg Chapter, Rotary Club Records, 1965/19981
- Dorothy H. Bodell Papers, 1850/19961
- Elizabeth Kent Adams Papers, 1922/19871
- George Green Shackelford Papers, 1899/1990, bulk 1955/19891
- Hard Times Blues Collection, 1966/20191
- Harry W. Sanders Papers, 1913/19811
- Historical Maps Collection, 1500/20231
- Independent Order of St. Luke Records, 1877/19701
- James J. Pandapas Audiotape and Papers, 1966/19971
- John R. Hutcheson Family Collection, 1890/1969, bulk 1930/19501
- Joseph F. Ware Collection, 1900/1971, bulk 1915/19201
- Leonard J. Currie Papers, 1920/20011
- Lucy Lee Lancaster Papers, 1915/19891