- A. H. Hand Papers, 1835/20092
- A. L. McLeod Papers, 1964/19662
- A. Willis Robertson Papers, 1921/1988, bulk 1946/19661,211
- Adagio Press Collection, 1957/19934
- Adam Empie Papers, 1811/2004, bulk 1811/18503
- Adele Blow Chatfield-Taylor family papers, 1899/197722
- African American GI's Vietnam and West Germany Scrapbook, 1960/19691
- Albert E. Garrett, Jr. scrapbook, 1927/19741
- Albert E. Haak Scrapbook, 1947/19772
- Alberto Runge Neo-Nazi Collection, 1958/19651
- Alfred R. Armstrong Papers, 1928/19761
- Alumni Association Photograph Collection, 1960/2010, bulk 1970/19901
- Alumni Association Records, 1833/2014, bulk 1950/200579
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/196025
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/197936