- IAWA Small Collections,, 1907/201313
- IAWA: International Archive of Women in Architecture Records, 1967/2013, bulk 1985/20082
- Ignorance Club collection, 1908/20241
- Imogene M. King Papers, 1948/20161
- Independent Order of St. Luke Records, 1877/197016
- Index to Publications regarding West Virginia Trains, Railroads, and Railroad Companies, 1954/19721
- Inge Horton Architectural Collection, 1964/199991
- Ingleside Book Club Records, 1923/20231
- Institute for the History of Technology and Industrial Archaeology Records, 1875/2005, bulk 1980/200571
- Institute for the History of Technology and Industrial Archaeology, Records regarding Blair Mountain, 1906/1992, bulk 1990/19921
- Institute of Southern Culture, 1955/19768
- Institute on the Teaching of Latin Records, 1938/1980, bulk 1938/19802
- Instructive Visiting Nurses Association records, 1902/199937
- Intercollegiate Athletics Records, 1930/2023, bulk 1975/200011
- Intercollegiate Athletics records, 192018