- C. Harrison Mann, Jr. map collection1
- Charlotte Bowers Nelson papers1
- Civil War Collection1
- G. William Whitehurst Papers1
- James I. Robertson Jr. Papers1
- Judith Fenner Barnard Collection1
- Louis Watson Chappell (1890-1981), Folklorist, Research Papers, Sound Recordings, and Other Material1
- Mann-Hutchinson Family Correspondence1
- Pocahontas Mines Collection1
- Post Family letters1
- Smith-Riffe Collection, History and Genealogy of Lower New River Valley1
- Thornton Tayloe Perry, Collector, Papers1
- United Mine Workers of America, Health and Retirement Funds, Records1
- William and Anne Fleming Family papers1