- Alvin D. Chandler Naval Record, 1925/19511
- Alvin Duke Chandler Papers, 1896/1984, bulk 1950/19603
- American Association of University Professors, College of William and Mary Chapter Records, 1924/1979, bulk 1924/197915
- American Association of University Women Records. William & Mary Chapter, 1934-1970, 1934/19701
- Amos Koontz Papers I, 1809/1965, bulk 1936/19653
- Amos Koontz Papers II, 1865/197039
- Anatole and Vladimir Kalichevsky Papers, 1871/19552
- Angel of Mt. Shavano Post 3820 (Veterans of Foreign Wars, Salida, Co.) Ladies Auxiliary Minute Book, 1948/19501
- Ann Little Papers, 1947/19672
- Anna Lou Jose Papers, 1905-1936, 1964, 1905/19641
- Anne H. Cutler Papers, 1930/2013, bulk 1954/20009
- Anne T. Chapman Papers, 1884/19543
- Anne and Alan Morledge Collection, 1946/2005, bulk 1969/19881
- Anson Du Puy Van Buren letters, 1863/19971
- Aquilla Matthews papers, 1925/19846