- Thomas L. Williams collection, 1940/19901,316
- Siler Family Papers, 1848/19681,155
- O.W. Riegel Papers, 1900/1992824
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025664
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974624
- Dabney Lancaster and Lancaster Family Records, 1848/1974482
- A. Willis Robertson Papers, 1921/1988, bulk 1946/1966470
- Gregory A. Prince Mormon Studies Collection, 1813/2020435
- West Virginia University, President's Office, Records, 1864/1989367
- John T. Parsons Papers, 1910/2000354
- The University of Virginia Anatomy Laboratory Lantern Slides collection, 1920/1965325
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/1997298
- American Public Transportation Association records, 1898/1999277
- Papers of the Superintendent and Resident Director, 1850/1996260
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969254