- Thomas L. Williams collection, 1940/19901,316
- Siler Family Papers, 1848/19681,153
- O.W. Riegel Papers, 1900/1992866
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025670
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974498
- Gregory A. Prince Mormon Studies Collection, 1813/2020435
- A. Willis Robertson Papers, 1921/1988, bulk 1946/1966386
- The University of Virginia Anatomy Laboratory Lantern Slides collection, 1920/1965325
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/1997291
- West Virginia University, President's Office, Records, 1864/1989268
- John T. Parsons Papers, 1910/2000261
- American Public Transportation Association records, 1898/1999256
- Records of the Office of the President, John Redd Hutcheson, 1917/1962254
- Papers of the Superintendent and Resident Director, 1850/1996245
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969243