- U.S. Forest Service, George Washington National Forest, Dry River District records, 1917/19944
- U.S. Navy China Station photograph album, 1938/19452
- U.S.S. Attala Papers, 1945/19462
- UR's 175th Anniversary Collection, 1997/20081
- USO Club (Williamsburg, Va.) Collection, 1943/19462
- USS Hyades Shipmates' Reunion Collection, 1940/20122
- USS Vulcan (AR-5) Collection, 1898/198513
- USS West Virginia, Navy Uniform of Granville R. Williams, 1941/20011
- USS West Virginia, Scrapbook and Memorabilia, 1941/19911
- USS West Virginia, Scrapbook and Other Material of William Hand, 1934/1988, bulk 1934/19371
- Ukrainian National Association. Assembly No. 29 (Nanticoke, Pa.) Records, 1907/19461
- Ulysses Grant Carter, Collector, Papers, Photographs, and Movie Films, 1928/19709
- Union Baptist Church Records, Hopewell, Virginia, 1935/20071
- Union Carbide Corporation, Hawk's Nest Project, Papers, 1873/19662
- Unitarian Universalist Church of Norfolk Records, 1866/2011, bulk 1950/199027