- U.S. Forest Service, George Washington National Forest, Dry River District records4
- U.S. Navy China Station photograph album2
- U.S.S. Attala Papers2
- UR's 175th Anniversary Collection1
- USO Club (Williamsburg, Va.) Collection2
- USS Hyades Shipmates' Reunion Collection2
- USS Vulcan (AR-5) Collection13
- USS West Virginia, Navy Uniform of Granville R. Williams1
- USS West Virginia, Scrapbook and Memorabilia1
- USS West Virginia, Scrapbook and Other Material of William Hand1
- Ukrainian National Association. Assembly No. 29 (Nanticoke, Pa.) Records1
- Ulysses Grant Carter, Collector, Papers, Photographs, and Movie Films9
- Union Baptist Church Records, Hopewell, Virginia1
- Union Carbide Corporation, Hawk's Nest Project, Papers2
- Unitarian Universalist Church of Norfolk Records27