- Thomas L. Williams collection, 1940/19901,315
- Siler Family Papers, 1848/19681,161
- Writers' Program in West Virginia Records, 1850/1942, bulk 1935/19421,133
- O.W. Riegel Papers, 1900/1992897
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974849
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025661
- Gregory A. Prince Mormon Studies Collection, 1813/2020429
- The University of Virginia Anatomy Laboratory Lantern Slides collection, 1920/1965325
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/1997286
- W. Jett Lauck papers, 1900/1952255
- Papers of the Superintendent and Resident Director, 1850/1996234
- American Public Transportation Association records, 1898/1999228
- Emory L. Kemp Papers regarding Industrial History, 1735/2021222
- James Wooddell, Compiler, Genealogy Research Papers, 1970/2000221
- A. Willis Robertson Papers, 1921/1988, bulk 1946/1966217