- Writers' Program in West Virginia Records, 1850/1942, bulk 1935/19421,173
- Siler Family Papers, 1848/19681,161
- O.W. Riegel Papers, 1900/1992682
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025625
- Federal Theatre Project collection, 1885/1986, bulk 1935/1939601
- W. Jett Lauck papers, 1900/1952518
- Gregory A. Prince Mormon Studies Collection, 1813/2020427
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974422
- West Virginia University, President's Office, Records, 1864/1989417
- The University of Virginia Anatomy Laboratory Lantern Slides collection, 1920/1965325
- Farrier Family Papers, 1894/1972290
- Willis Guy Tetrick, Jr. Genealogy Research Papers, 1708/1997289
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969248
- Rush Dew Holt (1905-1955) Papers, 1840/2003, bulk 1918/1955244
- Emory L. Kemp Papers regarding Industrial History, 1735/2021217