- Alan Clarke Railroad Research Papers, 1861/201223
- Alston Gordon Dayton Papers, 1846/19391
- Armstead L. Robinson papers, 1848/2001, bulk 1967/19929
- Arthur S. Dayton Correspondence and Catalogs regarding Purchase of Rare Books, 1898/2007, bulk 1923/19591
- Bernard McGregor, Professor of Music, Papers, 1890/19681
- Blair family papers, 1821/194915
- Braxton County (W. Va.) Court Records and Miscellaneous Papers, 1830/195327
- Charles H. Ambler (1876-1957) Papers, 1913/19571
- Charleston Gazette Publishing Company Records and Chilton Family Papers, 1884/20181
- Clarence L. Musgrave Papers, 1839/19371
- Davis Coal and Coke, Coal Mining and Railroad Company, Records, 1890/19804
- Dr. William A. Neal Papers, 1880/20161
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/18751
- Emory L. Kemp Papers regarding Industrial History, 1735/20218
- Ethel Fike Friend, Teacher, Papers, 1884/1993, bulk 1937/19932