- Blair family papers, 1821/19495
- Carter Glass Papers, 1820/194612
- Charles M. Robinson and Principals Architectural Records, 1855/20121
- Duke family law firm papers, 1820/19591
- Edwin S. Cohen papers, 1924/1995, bulk 1946/19891
- Fred O. Seibel Editorial Cartoonist's Research
Collection, ca. 1920 -
19681
- Herbert Friedman Holocaust materials, 1924/20062
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/18655
- John W. Warner papers, 1967/2009, bulk 1967/20082
- Lewis M. Dabney III papers on Edmund Wilson; William Faulkner and the Yoknapatawpha; and Crystal Ross and John Dos Passos., 1895/20053
- Milton L. Grigg Papers, 1929/19982
- University of Virginia Medical Center records, 1857/20245
- University of Virginia School of Medicine records, 1825/20204
- William Faulkner Collection, 1824/200625