- Siler Family Papers, 1848/19681,095
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025596
- Gregory A. Prince Mormon Studies Collection, 1813/2020416
- W. Jett Lauck papers, 1900/1952405
- West Virginia University, President's Office, Records, 1864/1989347
- G. Walter Mapp Papers, 1873/1941246
- O.W. Riegel Papers, 1900/1992233
- Farrier Family Papers, 1894/1972199
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974196
- Ward Engineering Company Archives and Manuscripts, 1871/1977192
- Emory L. Kemp Papers regarding Industrial History, 1735/2021185
- Records of the Office of the President, Julian A. Burruss, 1906/1946185
- duPont family papers, 1767/1982180
- Duke family law firm papers, 1820/1959175
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969174