- A.J. Morrison Collection, 1754/19751
- Brock Family Certificate Collection, 1870/19541
- Dr. Herbert J. Sipe, Jr. Papers, 1927/20191
- Elizabeth Carrington Eggleston Papers, 1899/19941
- Emma Venable Scrapbook Collection, 1926/19491
- Hampden-Sydney Diploma Collection, 1775/19741
- Hampden-Sydney Library Records, 1930/20121
- J. D. Eggleston Papers, 1750/19521
- Paul L. Grier Vertical Files, 1775/19881
- Records of Phi Beta Kappa, 1930/19521
- Records of the Philanthropic, Union, and Union-Philanthropic Literary Societies, 1789/20071
- Rev. S.M. Engle Papers, 1865/19371
- Sessional Records of South-Central Virginia Churches, 1760/19921
- Walter Taylor Reveley II collection, 1917/19921