- U.S. Forest Service, George Washington National Forest, Dry River District records, 1917/19947
- U.S. Forest Service, George Washington National Forest, Lost River and Massanutten Working Circles Reports, 1912/19402
- U.S. Works Progress Administration, West Virginia Historic Records Survey, Records, 1930/19391
- UR's 175th Anniversary Collection, 1997/20081
- USS Vulcan (AR-5) Collection, 1898/19851
- Ukrainian National Association. Assembly No. 29 (Nanticoke, Pa.) Records, 1907/19461
- Ulysses Grant Carter, Collector, Papers, Photographs, and Movie Films, 1928/19702
- Uneeda Trade Cards and Handwritten Recipes, 19302
- Union Carbide Corporation, Hawk's Nest Project, Papers, 1873/19662
- Unitarian Universalist Church of Norfolk Records, 1866/2011, bulk 1950/199016
- United Confederate Veterans Collection, 1893/19383
- United Daughters of the Confederacy Collection, 1920/19391
- United Daughters of the Confederacy Records (MS155), 1919/19882
- United Daughters of the Confederacy Williamsburg (Va.) records, 1890/199810
- United Daughters of the Confederacy, Dr. Harvy Black Chapter Records, 1862/201016