- Siler Family Papers, 1848/19681,152
- Long/Trail Southeastern West Virginia Historical Records, 1870/2025601
- Gregory A. Prince Mormon Studies Collection, 1813/2020420
- Philip S. Hench Walter Reed Yellow Fever collection, 1800/1998, bulk 1863/1974404
- W. Jett Lauck papers, 1900/1952378
- Edward L. Stone/Borderland Coal Company Papers
1895-1937368
- Farrier Family Papers, 1894/1972362
- The University of Virginia Anatomy Laboratory Lantern Slides collection, 1920/1965325
- G. Walter Mapp Papers, 1873/1941291
- Episcopal Diocese of Southwestern Virginia Records, 1866/2004, bulk 1919/1969239
- West Virginia University, President's Office, Records, 1864/1989232
- Records of the Office of the President, Julian A. Burruss, 1906/1946226
- Duke family law firm papers, 1820/1959212
- Emory L. Kemp Papers regarding Industrial History, 1735/2021200
- Bailey-Law Collection, 1825/1971189