- U.S. Forest Service, George Washington National Forest, Dry River District records4
- U.S. Forest Service, George Washington National Forest, Lost River and Massanutten Working Circles Reports2
- U.S. Patent 1374478: Self-Operating Mine-Doors for Locomotives1
- UR's 175th Anniversary Collection1
- USS Vulcan (AR-5) Collection3
- Ukrainian National Association. Assembly No. 29 (Nanticoke, Pa.) Records1
- Union Carbide Corporation, Hawk's Nest Project, Papers2
- Unitarian Universalist Church of Norfolk Records14
- United Confederate Veterans Collection8
- United Daughters of the Confederacy Collection1
- United Daughters of the Confederacy Records (MS155)2
- United Daughters of the Confederacy Williamsburg (Va.) records8
- United Daughters of the Confederacy, Dr. Harvy Black Chapter Records16
- United Daughters of the Confederacy, General Jenkins Chapter, Scrapbooks of Records1
- United Daughters of the Confederacy, Radford, VA Chapter Records3