- Attorney's Suit and Collection Record, 1896/19292
- Augustus Smith Family Collection, 1864/19262
- Aviation Brochures and Pamphlets Collection, 1910/19581
- Bailey-Law Collection, 1825/1971164
- Baughman Family Papers, 1837/19686
- Beattie Family University Memorabilia, 1875/19592
- Bell, Kent, Cloyd, Withrow Family Collection, 1780/199818
- Benjamin Cottrell Papers, 1910/19834
- Benjamin Huddle Diary, 1861/20062
- Bert T. Wilson Papers, 1889/19263
- Beulah O. Allen Collection, 1905/1992, bulk 1920/19701
- Bigler-Sessler-John Family Papers, 1752/19251
- Black, Kent, and Apperson Family Papers, 1779/198416
- Blacksburg Baptist Church Records, 1894/20076
- Blacksburg Deaths Journal, 1917/19472