- A. J. Davis Family Collection, 1874/2007, bulk 1874/19071
- Aaron Family Collection, 1908/19271
- Adam Finch Collection, 1891/19331
- Adam T. Finch Papers, 1895/19261
- Adin B. Underwood Papers, 1861/19261
- Agricultural Extension Service Records, 1914/19801
- Al Gross Papers, 1909/20001
- Alan Campbell Cameron Papers, 1914/19221
- Albert L. Sturm Papers, 1904/19881
- Alexander Farish Robertson Papers, 1867/19311
- Alexander W. Brown Diaries, 1904/19211
- Alfred C. Payne Collection, 1917/20031
- Alfred W. Lawson Collection, 1913/19481
- Alleghany Chapter, National Society of the Daughters of the American Revolution Records, 1890/20221
- Ambrose L. Snavely Papers, 1903/19521