- A. D. Lough correspondence, 1902/19201
- A.S. Hammack papers, 1864/19541
- Affidavits for Ardent Spirits Collection, 1916/19171
- Barnhart Family Papers, 1836/19441
- Bethlehem Stone Church Records, 1844/20111
- Bettie Hiter Willis Papers, 1864/19421
- Blackley Family papers, 1830/20201
- Bowman Family Papers, 1765/19981
- Bridgewater Voter Roll, 1902/19481
- Brown Family papers, 1872/19191
- Carrie Bishop Scrapbook, 1914/19181
- Catlett Family Papers, 1850/1933, bulk 1901/19291
- Charles Grattan Price Jr. and Don W. Thomas collection on the Chesapeake Western Railway, 1872/19961
- Charles Grattan Price Jr. collection on Tweetsie and the Shenandoah Central Railroad, 1916/1997, bulk 1948/19561
- Charles T. Smith photographs, 1880/2007, bulk 1990/19991