- U.S. Army Corps of Engineers, Photographs of Operations in Pennsylvania, Ohio, New York, and the Pacific Northwest, 1914/19191
- U.S. Forest Service, George Washington National Forest, Lost River and Massanutten Working Circles Reports, 1912/19402
- UR's 175th Anniversary Collection, 1997/20081
- USS Vulcan (AR-5) Collection, 1898/19853
- Ukrainian National Association. Assembly No. 29 (Nanticoke, Pa.) Records, 1907/19461
- Union Carbide Corporation, Hawk's Nest Project, Papers, 1873/19662
- Unitarian Universalist Church of Norfolk Records, 1866/2011, bulk 1950/199013
- United Confederate Veterans Collection, 1893/19388
- United Daughters of the Confederacy Williamsburg (Va.) records, 1890/19987
- United Daughters of the Confederacy, Dr. Harvy Black Chapter Records, 1862/201014
- United Daughters of the Confederacy, General Jenkins Chapter, Scrapbooks of Records, 1899/19721
- United Daughters of the Confederacy, Radford, VA Chapter Records, 1896/19482
- United Daughters of the Confederacy, Southern Cross of Honor Records, 1905/19417
- United Daughters of the Confederacy, Turner Ashby Chapter Records, 1896/19915
- United Mine Workers Records at Cornell University, 1899/19271