- IAWA Small Collections,, 1907/20134
- IAWA: International Archive of Women in Architecture Records, 1967/2013, bulk 1985/20081
- Ida Marion Gilliam Diaries, 1905/19152
- Ignorance Club collection, 1908/20242
- Independent Order of St. Luke Records, 1877/19705
- Inge Horton Architectural Collection, 1964/1999101
- Institute for the History of Technology and Industrial Archaeology Records, 1875/2005, bulk 1980/200526
- Institute for the History of Technology and Industrial Archaeology, Records regarding Blair Mountain, 1906/1992, bulk 1990/19921
- Instructive Visiting Nurses Association records, 1902/199910
- Internal Library Records, 1923/20231
- International Association for Identification Records, 1842/2012, bulk 1910/195946
- International Order of Odd Fellows, Lodge 134, Ledgers, 1892/19281
- Ira E. Robinson Papers, 1818/19301
- Ira E. Robinson Papers, 1869/19511
- Iron Gate, Virginia, Ledgers,, 1892/19311