- A. J. Davis Family Collection, 1874/2007, bulk 1874/19076
- Aaron Family Collection, 1908/19272
- Adam Finch Collection, 1891/19332
- Adam T. Finch Papers, 1895/19262
- Adin B. Underwood Papers,, 1861/19262
- Agricultural Extension Service Records, 1914/19801
- Al Gross Papers, 1909/20001
- Alan Campbell Cameron Papers, 1914/19222
- Albert L. Sturm Papers, 1904/19883
- Alexander Farish Robertson Papers, 1867/193130
- Alexander W. Brown Diaries, 1904/19212
- Alfred W. Lawson Collection, 1913/19481
- Alleghany Chapter, National Society of the Daughters of the American Revolution Records,, 1890/202211
- Ambrose L. Snavely Papers, 1903/19523
- American Locomotive Company/Baldwin Locomotive Works Illustrations, 1900/19251