- C-SPAN records, 1809/2012, bulk 1978/20124
- C. C. Driver and Co. Ledger, I, 1910/19121
- C. Edwin Baker Papers, 1886/2013, bulk 1970/20091
- C. Eugene Rowe Papers, 1949/19871
- C. F. Tucker Brooke (1883-1946) Papers, 1870/1989, bulk 1895/19451
- C. Harrison Mann, Jr. Map Collection, 1579/19611
- C. Harrison Mann, Jr. map collection, 1579/19611
- C. Harrison Mann, Jr. papers, 1832/19792
- C. L. Worthington Papers, 1752/19384
- C.F. Millspaugh, LIVING FLORA OF WEST VIRGINIA, Correspondence, 19121
- C.M. Cornwell Papers, 1840/19191
- C.W. Cramer Papers, 1894/19181
- Cabell Family Papers, 1693/1913, bulk 1743/18233
- Cabinet Photograph of Unknown Mountain and Valley Scene, 1880/19201
- Cadet Life, Organizations, and Activities, 18452