- Andrew Nelson Campbell Papers, 1854/19281
- Andrew Nelson Campbell, Civil War Veteran and Monroe County Politician, Papers, 1856/19321
- Brand Family Papers, 1861/19241
- Clark Family Correspondence, 1885/19391
- Clement Ross Jones (1871-1939) Papers, 1890/19321
- Courtney Family Papers, 1804/19201
- David Dial, Collector, Glass Plate Negatives of West Virginia University Agricultural Experiment Station Projects and Other Subjects, 1891/19121
- Dr. Barbara Howe, Professor, Papers, 1856/2025, bulk 1964/20251
- Emory L. Kemp Papers regarding Industrial History, 1735/20211
- Ethel Fike Friend, Teacher, Papers, 1884/1993, bulk 1937/19931
- Festus P. Summers (1895-1971), Historian, Papers, 1843/19711
- G. Harry Bayles Papers, 1890/19551
- General Education Board Records, 1901/19671
- Gideon D. Camden (1805-1891) Papers, 1784/19581
- Guy B. Young Papers, 1880/19401