- Alexandria History Collection (MS240), 1767/200810
- Alexandria Library Company Records (MS002), 1794/20072
- Armistead Boothe Papers (MS164), 1803/199010
- Boush/Asher Family Collection (MS234), 1856/19494
- Brotherhood of Locomotive Engineers, Robert Andrews Dist. 417 (MS204), 1886/19041
- Cameron Club Collection (MS077), 1895/19443
- Cazenove Family Papers (MS212), 1786/19703
- Chapman Family Collection (MS274), 1828/19634
- Chapman-Southerland Collection (MS409), 1878/19133
- Charles L. Sampson Collection (MS126), 1841/19865
- Curtin Family Papers (MS101), 1885/20003
- Daniel O'Sullivan Collection (MS141), 1850/19122
- Edith Moore Sprouse Papers (MS313), 1960/20031
- Eleanor Lee Templeman Collection (MS061), 1810/19901
- Esther Holliday Green Collection (MS073), 1859/198211