- A. E. Dick Howard papers, 1928/20171
- African American man tintype portrait, 1865/19001
- Albemarle and Chesapeake Canal Company annual report of the President and the Directors, 18891
- Albert Frederick Wilson papers, 1840/19343
- Albert R. Gallatin papers, 1795/18281
- Albert Taylor Bledsoe and Sophia Bledsoe Herrick letters, 1858/19081
- Alderman family papers, 1779/19618
- Alexander Family Papers
1800-18904
- Alfred C. Garnett, Jr. Papers
1868-19453
- Alfred Oscar Elzner sketch book and album, 1883/19231
- Alfred Spates Papers
1843-19093
- Alice and Phoebe Cary Collection
1858-18901
- Allen Caperton Braxton Papers3
- Amelie (Rives) Troubetzkoy Collection1
- Anna Maria Hickman Otis Mead Chalmers family papers, 1821/189719