- D. Boston Stewart Papers, 1782/1919, bulk 1862/19061
- D. J. Watkins Yellow Fever Epidemic Papers, 18881
- D.W. Rogers Manuscripts, 1832/19021
- Dabney Lancaster and Lancaster Family Records, 1848/19745
- Dade Family Papers, 1826/1910, bulk 1826/18432
- Daingerfield Papers, 1833/19301
- Daisy Bacon Papers, 1857/19864
- Dana Brothers Papers, 1871/18891
- Dana Harmon Papers, 1885/19163
- Daniel Bedinger Lucas Papers, 1812/18244
- Daniel J. Meador papers, 1959/20031
- Daniel O'Sullivan Collection (MS141), 1850/19126
- Daniel Stickley Account Books, 1834/19121
- Daniel Stickley Papers, 1829/19122
- Danske Dandridge (1854-1914) Letters, 1869/19131