- Adolphus DeBussey, Soldier, Civil War Letters, 1861/1998, bulk 1861/18711
- Adolphus P. Howard Papers, 1850/19381
- Adolphus P. Howard Papers, 1854/19041
- Advisory Committee Research Collection, 1772/20171
- African American Stereoview Collection, 1860/19011
- African American man tintype portrait, 1865/19001
- African and African American photograph collection, 1850/19451
- Aileen Shafer, Collector, Material regarding African-Americans, 1829/18841
- Alabama Collection, 1823/18931
- Alan Clarke Railroad Research Papers, 1861/20121
- Albemarle County ledger book, 1871/18801
- Albert C. Swindler Papers, 1862/1929, bulk 1862/18641
- Albert Frederick Wilson papers, 1840/19341
- Albert M. Reese (1872-1965) Papers, 1873/19541
- Albert Taylor Bledsoe and Sophia Bledsoe Herrick letters, 1858/19081