- Siler Family Papers, 1848/19681,147
- Early Records of the Mount Vernon Ladies' Association, 1853/1951, bulk 1853/1875214
- Gregory A. Prince Mormon Studies Collection, 1813/2020160
- John L. Nau III Civil War History Collection, 1806/1988, bulk 1861/1865159
- Roy Bird Cook (1886-1961), Collector, Papers, 1679/1984, bulk 1840/1960144
- Monongalia County (W. Va.) Court Records and Miscellaneous Papers, 1774/1954143
- Emory L. Kemp Papers regarding Industrial History, 1735/2021142
- Galt Papers (III), 1750/1991141
- Restoration Files for the Historic Structures Report, 1750/2005115
- Ohio County (W. Va.) Court Records and Miscellaneous Papers, 1772/1954, bulk 1777/1930109
- Edward "Teddy" Bolton Tucker Papers, 1760/2007, bulk 1800/1900107
- Historical Photograph Collection, 1850/2010102
- Sheet Music Collection, 1827/1974101
- James I. Robertson Jr. Papers, 1849/201196
- Tyler Family Papers, Group D, 1939/195176